Mouse Early Activation Antigen CD69 (CD69) Protein
1235€ (100 µg)
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935106861
info@markelab.com
name
Mouse Early Activation Antigen CD69 (CD69) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693012
tested applications
SDS-PAGE
Description
Mouse CD69 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse Cd69 (NP_001028294.1) (Gly64-Arg199) was expressed with the Fc region of human IgG1 at the N-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Early Activation Antigen CD69 (CD69) |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 44.1 kDa Sequence Fragment: Gly64-Arg199 Tag: N-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_001028294.1 |
| Alias | AIM,EA1,MLR-3,CLEC2C,GP32/28,BL-AC/P26,Early activation antigen CD69,Activation inducer molecule,C-type lectin domain family 2 member C |
| Background | Protein CD69 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD69, also known as activation inducer molecule (AIM), is a type II transmembrane glycoprotein expressed primarily on the surface of activated immune cells, including T cells, B cells, natural killer (NK) cells, macrophages, and dendritic cells. CD69 is one of the earliest surface markers to be upregulated after lymphocyte activation, making it a widely used marker of immune cell activation. Its expression can be induced by a variety of stimuli, including antigen recognition, cytokines, and inflammatory signals. In addition to its role in immune activation, CD69 also plays critical roles in immune homeostasis, inflammation regulation, and tissue retention of lymphocytes. It functions as a key regulator of immune responses, particularly through its involvement in the migration and localization of immune cells to sites of inflammation or infection. Furthermore, CD69 is important in maintaining tissue-specific immunity in organs such as the lungs and intestines, where resident immune cells contribute to mucosal defense.
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