Mouse Early Activation Antigen CD69 (CD69) Protein

Este producto es parte de CD69 - CD69 molecule
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1235€ (100 µg)

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935106861
info@markelab.com
name
Mouse Early Activation Antigen CD69 (CD69) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691598
tested applications
SDS-PAGE

Description

Mouse CD69 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse Cd69 (NP_001028294.1) (Asn62-Arg199) was expressed with a polyhistidine tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Early Activation Antigen CD69 (CD69)
Host
HEK293 cells
Origin
Mouse
Observed MW
Molecular Weight: 17.3 kDa
Sequence Fragment: Asn62-Arg199
Tag: C-terminal His tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 85% (SDS-PAGE)
Size 1
100 µg
Form
 
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NP_001028294.1
Alias
AIM,EA1,MLR-3,CLEC2C,GP32/28,BL-AC/P26,Early activation antigen CD69,Activation inducer molecule,C-type lectin domain family 2 member C
Background
Protein CD69
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD69, also known as activation inducer molecule (AIM), is a type II transmembrane glycoprotein expressed primarily on the surface of activated immune cells, including T cells, B cells, natural killer (NK) cells, macrophages, and dendritic cells. CD69 is one of the earliest surface markers to be upregulated after lymphocyte activation, making it a widely used marker of immune cell activation. Its expression can be induced by a variety of stimuli, including antigen recognition, cytokines, and inflammatory signals. In addition to its role in immune activation, CD69 also plays critical roles in immune homeostasis, inflammation regulation, and tissue retention of lymphocytes. It functions as a key regulator of immune responses, particularly through its involvement in the migration and localization of immune cells to sites of inflammation or infection. Furthermore, CD69 is important in maintaining tissue-specific immunity in organs such as the lungs and intestines, where resident immune cells contribute to mucosal defense.

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