Mouse Downs Syndrome Cell Adhesion Molecule Like 1 (DSCAML1) ELISA Kit

Este producto es parte de DSCAM - DS cell adhesion molecule
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Downs Syndrome Cell Adhesion Molecule Like 1 (DSCAML1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx389102
tested applications
ELISA

Description

Mouse Downs Syndrome Cell Adhesion Molecule Like 1 (DSCAML1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Downs Syndrome Cell Adhesion Molecule Like 1 (DSCAML1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Downs Syndrome Cell Adhesion Molecule Like 1 (DSCAML1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.094 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q4VA61
Alias
DSCAM2,Down syndrome cell adhesion molecule-like protein 1,Down syndrome cell adhesion molecule 2
Background
Elisa kits for DSCAML1
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

DS cell adhesion molecule like 1 (DSCAML1) DSCAML1, a member of the immunoglobulin superfamily, is a transmembrane protein that shares structural and functional similarity with DS cell adhesion molecule (DSCAM). It plays a vital role in neural development, particularly in axon guidance, dendritic self-avoidance, and synapse formation. DSCAML1 is involved in ensuring proper neuronal wiring by mediating selective cell-cell adhesion through homophilic binding, which is critical for preventing overlapping dendrites of the same neuron. It is highly expressed in the developing central nervous system, particularly in regions such as the retina and olfactory bulb. Mutations in DSCAML1 have been associated with neurodevelopmental disorders, including epilepsy, underscoring its role in maintaining neural circuit stability. The protein consists of multiple immunoglobulin-like and fibronectin domains, enabling diverse interactions that support cellular connectivity and signaling.

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