Mouse Docking Protein 1 (DOK1) ELISA Kit

Este producto es parte de DOK - Docking protein
Mouse Docking Protein 1 (DOK1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOK1

proveedor

Abbexa

reference

abx389096

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Docking Protein 1 (DOK1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse DOK1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Docking protein 1 (DOK1) serves as an adaptor protein involved in cellular signaling pathways, particularly those linked to tyrosine kinase receptors and cytokine receptors. DOK1 lacks intrinsic enzymatic activity but facilitates signal transduction by linking membrane-bound receptors to downstream effectors. It plays a critical role in regulating cell proliferation, differentiation, and apoptosis by acting as a negative regulator of mitogenic signaling pathways. DOK1 is highly expressed in hematopoietic cells and is instrumental in immune responses. Dysregulation of DOK1 has been implicated in oncogenesis, particularly in hematologic malignancies, where it acts as a tumor suppressor by inhibiting excessive cellular proliferation and survival signals. Its interactions with Ras-GAP and other signaling molecules underline its importance in maintaining cellular homeostasis.

Características del producto

category

ELISA Kits


immunogen target

Docking Protein 1 (DOK1)


reactivity

Mouse


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 46.9 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

Downstream of tyrosine kinase 1,P62DOK, pp62


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOK1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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