Mouse DENN domain-containing protein 2C (DENND2C) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse DENN domain-containing protein 2C (DENND2C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx510097
tested applications
ELISA
Description
Mouse DENN domain-containing protein 2C (DENND2C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse DENN domain-containing protein 2C concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DENN domain-containing protein 2C (DENND2C) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6P9P8 |
| Alias | dJ1156J9.1 |
| Background | Elisa kits for DENND2C |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DENN domain containing 2C (DENND2C) acts as a guanine nucleotide exchange factor (GEF) for Rab GTPases, regulating intracellular vesicle trafficking and membrane dynamics. DENND2C activates Rab9 by facilitating the exchange of GDP for GTP, enabling vesicular transport between late endosomes and the trans-Golgi network. This activity is essential for the sorting and trafficking of lysosomal enzymes and other cargo, maintaining cellular proteostasis. In addition to its role in endosomal transport, DENND2C contributes to signaling pathways that depend on membrane trafficking, including those involved in cell growth and stress responses. DENND2C is expressed in various tissues, but its activity is particularly significant in cells with high lysosomal turnover, such as macrophages and epithelial cells. Dysregulation of DENND2C has been linked to diseases involving lysosomal dysfunction, highlighting its importance in cellular homeostasis and adaptive responses.
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DENN Domain-Containing Protein 2C (DENND2C) Antibody
DENND2C Antibody is a Rabbit Polyclonal against DENND2C.
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DENND2C Antibody (HRP) is a Rabbit Polyclonal against DENND2C conjugated to HRP.
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DENND2C Antibody (FITC)
DENND2C Antibody (FITC) is a Rabbit Polyclonal against DENND2C conjugated to FITC.
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