Mouse Dedicator of cytokinesis protein 6 (DOCK6) ELISA Kit

Este producto es parte de DOCK - Dedicator of Cytokinesis
Mouse Dedicator of cytokinesis protein 6 (DOCK6) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOCK6

proveedor

Abbexa

reference

abx510798

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Dedicator of cytokinesis protein 6 (DOCK6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 6 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DOCK6 is a dual GEF for Rac1 and Cdc42, critical for cytoskeleton regulation, neurite outgrowth, and axonal growth. It facilitates actin and microtubule dynamics, influencing processes like neuronal development and fibroblast migration. DOCK6 mutations are associated with Adams-Oliver syndrome, characterized by limb and scalp defects due to impaired cell migration. It is expressed in neural and connective tissues, where it regulates cellular polarity and adhesion. DOCK6 interacts with Rac1 to drive membrane protrusion and lamellipodia formation. Knockdown studies show defects in axonal elongation and cellular migration, underscoring its role in tissue development and repair.

Características del producto

category

ELISA Kits


immunogen target

Dedicator of cytokinesis protein 6 (DOCK6)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

DOCK6, KIAA1395,AOS2, ZIR1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOCK6


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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