Mouse Dedicator of cytokinesis protein 6 (DOCK6) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DOCK6
proveedor
Abbexareference
abx510798Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Dedicator of cytokinesis protein 6 (DOCK6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
DOCK6 is a dual GEF for Rac1 and Cdc42, critical for cytoskeleton regulation, neurite outgrowth, and axonal growth. It facilitates actin and microtubule dynamics, influencing processes like neuronal development and fibroblast migration. DOCK6 mutations are associated with Adams-Oliver syndrome, characterized by limb and scalp defects due to impaired cell migration. It is expressed in neural and connective tissues, where it regulates cellular polarity and adhesion. DOCK6 interacts with Rac1 to drive membrane protrusion and lamellipodia formation. Knockdown studies show defects in axonal elongation and cellular migration, underscoring its role in tissue development and repair.
Características del producto
category
ELISA Kits
immunogen target
Dedicator of cytokinesis protein 6 (DOCK6)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
DOCK6, KIAA1395,AOS2, ZIR1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DOCK6
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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