Docking Protein 6 (DOCK6) Antibody

Name: Docking Protein 6 (DOCK6) Antibody
Brand: Abbexa
SKU: abx232496
Price: 364 EUR
Availability: OnlineOnly

Este producto es parte de DOCK - Dedicator of Cytokinesis

Pida mas información

935106861

info@markelab.com

Precio

364€ (100 µg)

Antibody anti-DOCK6

proveedor

Abbexa

reference

abx232496

Tested Applications

ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

DOCK6 Antibody is a Rabbit Polyclonal against DOCK6.

Background

DOCK6 is a dual GEF for Rac1 and Cdc42, critical for cytoskeleton regulation, neurite outgrowth, and axonal growth. It facilitates actin and microtubule dynamics, influencing processes like neuronal development and fibroblast migration. DOCK6 mutations are associated with Adams-Oliver syndrome, characterized by limb and scalp defects due to impaired cell migration. It is expressed in neural and connective tissues, where it regulates cellular polarity and adhesion. DOCK6 interacts with Rac1 to drive membrane protrusion and lamellipodia formation. Knockdown studies show defects in axonal elongation and cellular migration, underscoring its role in tissue development and repair.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Docking Protein 6 (DOCK6)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purity

≥ 95% (SDS-PAGE)

purification

Purified by immunogen affinity chromatography.

recommended dilution

WB: 1/200 - 1/1000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

size 1

100 µg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

DOCK6

dry ice

availability

Shipped within 5-12 working days.

alias

DOCK6, KIAA1395,AOS2, ZIR1

uniprot id

https://www.uniprot.org/uniprotkb/Q96HP0

gene id

https://www.ncbi.nlm.nih.gov/gene/57572

note

Concentration: 2 mg/ml - Validity: 12 months.

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Tested Applications

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reactivity

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status

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clonality

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proveedor

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reference

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Tested Applications

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