Mouse Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DOCK11
proveedor
Abbexareference
abx510779Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 11 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
DOCK11, also known as Zizimin2, is a GEF for Cdc42, regulating actin cytoskeleton dynamics, filopodia formation, and cell polarity. It is highly expressed in hematopoietic cells and supports processes like B-cell development, migration, and activation. DOCK11 is essential for lymphocyte trafficking and immune synapse formation, ensuring effective immune responses. It interacts with phosphoinositides for membrane localization and signaling. Dysregulation is linked to impaired immune functions, particularly in B lymphocytes, causing migration and adhesion defects. Studies in knockout models highlight its role in maintaining B-cell integrity and immune surveillance, underscoring its importance in hematopoietic cell biology.
Características del producto
category
ELISA Kits
immunogen target
Dedicator of cytokinesis protein 11 (DOCK11)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
ACG, ADMIDX, ZIZ2, bB128O4.1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DOCK11
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Human Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit
proveedor
Abbexareference
abx510778Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement o...
715€ (96 tests)
Ver másMouse Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit
proveedor
Abbexareference
abx510779Tested Applications
ELISAreactivity
Mousestatus
RUOMouse Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement o...
715€ (96 tests)
Ver más