Mouse DDB1- and CUL4-associated factor 17 (DCAF17) ELISA Kit
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Description
Mouse DDB1- and CUL4-associated factor 17 (DCAF17) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse DDB1- and CUL4-associated factor 17 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DDB1- and CUL4-associated factor 17 (DCAF17) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q3TUL7 |
| Gene ID | 75763 |
| Alias | C2orf37,C20orf37, |
| Background | Elisa kits for DCAF17 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DDB1 and CUL4 associated factor 17 (DCAF17) is a substrate receptor of the CUL4-DDB1 E3 ubiquitin ligase complex, involved in the regulation of protein ubiquitination and degradation. DCAF17 contains WD40 repeats, which mediate protein-protein interactions and the recognition of specific substrates for targeted degradation. Its expression pattern suggests roles in various tissues, particularly in processes related to cellular homeostasis and proteostasis. DCAF17 has been implicated in nuclear and cytoplasmic functions, including the maintenance of protein quality and the regulation of signaling pathways. Genetic studies indicate that DCAF17 may be involved in developmental processes, as mutations in its gene have been associated with craniofacial abnormalities and intellectual disability. The precise substrates and mechanisms of DCAF17's action remain areas of active investigation, but its role in the ubiquitin-proteasome system highlights its importance in maintaining cellular function and response to environmental stress.
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