Mouse Cytosolic carboxypeptidase-like protein 5 (AGBL5) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AGBL5
proveedor
Abbexareference
abx505005Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Cytosolic carboxypeptidase-like protein 5 (AGBL5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Cytosolic carboxypeptidase-like protein 5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AGBL5 functions as a tubulin deglutamylase, removing polyglutamate chains from the tails of microtubules to regulate their dynamics and functionality. It is predominantly expressed in the nervous system but is also present in other tissues, where it plays a role in axon development, neuronal signaling, and intracellular transport mechanisms. AGBL5 activity is essential for proper mitotic spindle formation, ensuring accurate chromosome segregation during cell division. Dysregulation of AGBL5 has been linked to neurodegenerative diseases, such as Alzheimer’s disease, due to the accumulation of hyperglutamylated tubulin that disrupts axonal transport. It has also been implicated in cancer progression, where alterations in microtubule dynamics can enhance cell motility and invasive potential. Further studies are ongoing to elucidate its broader physiological and pathological roles.
Características del producto
category
ELISA Kits
immunogen target
Cytosolic carboxypeptidase-like protein 5 (AGBL5)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CCP5,RP75
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AGBL5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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