Mouse Coronin-7 (CORO7) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits CORO7
proveedor
Abbexareference
abx508057Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Coronin-7 (CORO7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Coronin-7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Coronin 7 (CORO7) is a member of the coronin protein family, distinguished by its lack of actin-binding capability, unlike other coronins. Instead, it functions as an F-actin regulator involved in directing anterograde transport from the Golgi apparatus to endosomes. CORO7 localizes to the trans-Golgi network and is essential for maintaining Golgi apparatus morphology. Its recruitment to Golgi membranes requires Src kinase activity and the integrity of the AP-1 adaptor protein complex. CORO7 interacts with the μ1-subunit of AP-1 via a tyrosine-288-based sorting signal and is phosphorylated by Src kinase, which is crucial for its membrane targeting. Additionally, CORO7 undergoes K33-linked polyubiquitination via an E3 ligase complex, influencing its function in Golgi trafficking. Notably, CORO7 does not interact with actin or participate in actin-mediated processes but plays a significant role in vesicular trafficking pathways.
Características del producto
category
ELISA Kits
immunogen target
Coronin-7 (CORO7)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CRN7,POD1,70 kDa WD repeat tumor rejection antigen homolog,Coronin-7
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CORO7
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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