Mouse Contactin-6 (CNTN6) ELISA Kit

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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Contactin-6 (CNTN6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx507703
tested applications
ELISA

Description

Mouse Contactin-6 (CNTN6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Contactin-6 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetContactin-6 (CNTN6)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ9JMB8
Gene ID53870
AliasNB3,Neural recognition molecule NB-3,hNB-3,Contactin-6
BackgroundElisa kits for CNTN6
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Contactin 6 (CNTN6), also referred to as NB-3, is a neuronal cell adhesion molecule that is highly expressed in the brain and spinal cord during development. It regulates axon guidance, neuronal migration, and synapse formation, particularly in corticospinal tract development and cerebellar circuit organization. CNTN6 interacts with other contactins and neural receptors to facilitate synaptic connectivity and plasticity, contributing to the establishment of neural networks involved in motor control and coordination. Genetic studies have implicated CNTN6 in neurodevelopmental disorders such as autism spectrum disorders (ASD) and intellectual disability, where its dysregulation disrupts neuronal connectivity and cognitive functions. In addition to its roles in development, CNTN6 expression persists in the adult nervous system, suggesting ongoing functions in synaptic maintenance and plasticity. Structurally, CNTN6 features extracellular immunoglobulin-like and fibronectin type III domains, which mediate its adhesive and signaling interactions. Emerging research also highlights its potential involvement in neuropathological conditions, including neurodegenerative diseases and peripheral neuropathies.

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