Mouse E3 Ubiquitin-Protein Ligase CBL-B (CBLB) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CBLB
proveedor
Abbexareference
abx520104Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse E3 Ubiquitin Protein Ligase CBL-B (CBLB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse E3 ubiquitin-protein ligase CBL-B concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CBLB, another member of the CBL family, shares a similar function to CBL in ubiquitinating target proteins, but it has its unique set of substrates and regulatory roles. CBLB primarily regulates immune cell signaling, particularly in T and B cells, by modulating receptor signaling pathways involved in immune responses. It is involved in the regulation of T-cell receptor (TCR) signaling, and its activity helps in controlling the activation threshold of immune cells. Similar to CBL, CBLB can influence the stability of receptors and other signaling molecules by mediating their degradation. Altered expression or mutations in CBLB can affect immune responses, and it has been linked to autoimmune diseases and immune deficiencies.
Características del producto
category
ELISA Kits
immunogen target
E3 Ubiquitin-Protein Ligase CBL-B (CBLB)
reactivity
Mouse
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
13.7 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CBL-B,CBLB,Cbl-b, RNF56, ADMIO3, Nbla00127
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CBLB
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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