Mouse E3 Ubiquitin-Protein Ligase CBL-B (CBLB) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse E3 Ubiquitin-Protein Ligase CBL-B (CBLB) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx520104
tested applications
ELISA
Description
Mouse E3 Ubiquitin Protein Ligase CBL-B (CBLB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse E3 ubiquitin-protein ligase CBL-B concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | E3 Ubiquitin-Protein Ligase CBL-B (CBLB) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.2 pg/ml - 2000 pg/ml |
| Sensitivity | 13.7 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q3TTA7 |
| Alias | CBL-B,CBLB,Cbl-b, RNF56, ADMIO3, Nbla00127 |
| Background | Elisa kits for CBLB |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CBLB, another member of the CBL family, shares a similar function to CBL in ubiquitinating target proteins, but it has its unique set of substrates and regulatory roles. CBLB primarily regulates immune cell signaling, particularly in T and B cells, by modulating receptor signaling pathways involved in immune responses. It is involved in the regulation of T-cell receptor (TCR) signaling, and its activity helps in controlling the activation threshold of immune cells. Similar to CBL, CBLB can influence the stability of receptors and other signaling molecules by mediating their degradation. Altered expression or mutations in CBLB can affect immune responses, and it has been linked to autoimmune diseases and immune deficiencies.
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