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Mouse CASP8 And FADD Like Apoptosis Regulator (CFLAR) Protein
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935106861
info@markelab.com
Precio
225€ (10 µg)
Protein CFLAR
proveedor
Abbexareference
abx065746Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant CASP8 And FADD Like Apoptosis Regulator (CFLAR) is a recombinant Mouse protein produced in E. coli using Prokaryotic expression.
Background
CASP8 and FADD-like apoptosis regulator (CFLAR), also known as c-FLIP, is an important regulatory protein that modulates apoptosis, particularly in response to death receptor signaling. CFLAR is structurally related to the caspase family but lacks protease activity, allowing it to inhibit caspase-8 activation in the death receptor pathway. By binding to the death-inducing signaling complex (DISC), CFLAR blocks the activation of downstream apoptotic signaling, effectively acting as an inhibitor of apoptosis. This inhibition allows cells to evade cell death, and as such, CFLAR has been implicated in promoting cell survival in various cancers, as well as playing a role in immune responses.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
CASP8 And FADD Like Apoptosis Regulator (CFLAR)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CFLAR
dry ice
No
availability
Shipped within 5-7 working days.
alias
CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASP8 and FADD like apoptosis regulator, cFLIP
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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