Mouse Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) ELISA Kit

Este producto es parte de ADGRB - Adhesion G protein-coupled receptor B
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503499
tested applications
ELISA

Description

Mouse Brain-specific angiogenesis inhibitor 1 / BAI1 (ADGRB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Brain-specific angiogenesis inhibitor 1 / BAI1 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q3UHD1
Gene ID
107831
Alias
ADGRB1,BAI1,GDAIF
Background
Elisa kits for ADGRB1
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ADGRB1, also known as BAI1 (Brain-Specific Angiogenesis Inhibitor 1), is a member of the adhesion G protein-coupled receptor (GPCR) family predominantly expressed in the brain. It plays a critical role in inhibiting angiogenesis, promoting synaptic plasticity, and mediating phagocytic clearance of apoptotic cells and pathogens. Structurally, ADGRB1 contains multiple extracellular domains that facilitate interactions with matrix proteins and apoptotic cell markers. Dysregulation of ADGRB1 is associated with glioblastoma, as it suppresses tumor angiogenesis and growth, and its loss can contribute to tumor progression. Additionally, it has been implicated in synaptic function and neuronal health, with potential roles in neurodevelopmental disorders and neurodegeneration. ADGRB1’s ability to link extracellular signals to intracellular pathways highlights its importance in vascular regulation and brain function.

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