Mouse Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) Protein
208€ (10 µg)
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935106861
info@markelab.com
name
Mouse Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691374
tested applications
SDS-PAGE
Description
Mouse Bone Morphogenetic Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse Bone Morphogenetic Protein Receptor Type IA/Activin Receptor-like Kinase 3 is produced by our Mammalian expression system and the target gene encoding Gln24-Arg152 is expressed with a Fc, 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Bone Morphogenetic |
| Host | Human |
| Origin | Mouse |
| Observed MW | Molecular Weight: 42.2 kDa Sequence Fragment: Gln24-Arg152 Tag: C-terminal Fc tag and 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM PB, 150mM NaCl, pH7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | P36895 |
| Alias | Activin receptor-like kinase 3,ALK3,SKR5,ALK-3,CD292,ACVRLK3,BMPR-1A,Serine/threonine-protein kinase receptor R5 |
| Background | Protein BMPR1A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Bone morphogenetic protein receptor type 1A (BMPR1A) is a receptor for the bone morphogenetic proteins (BMPs), a subgroup of the transforming growth factor-beta (TGF-β) superfamily. BMPs are growth factors and cytokines that play critical roles in embryonic development, skeletal formation, organogenesis, and tissue homeostasis. BMPR1A, also known as ALK3 (Activin receptor-like kinase 3), specifically mediates BMP signaling by interacting with BMP ligands to activate intracellular pathways, influencing processes such as cell growth, differentiation, apoptosis, and repair. This receptor is essential for bone and cartilage development and has critical roles in several cell types across various tissues, with particularly strong influence in skeletal, cardiac, and gastrointestinal systems.
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