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On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Primary Antibodies
polyclonal
human,mouse,rat
bone morphogenetic protein receptor, type IA
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IF, IP
60 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BMPR1A
Activin receptor-like kinase 3,ALK3,SKR5,ALK-3,CD292,ACVRLK3,BMPR-1A,Serine/threonine-protein kinase receptor R5
This product is for research use only.
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Ver másOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kina...
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