Mouse Bone Morphogenetic Protein Receptor Type-1B (BMPR1B) Protein
1235€ (100 µg)
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Name
Mouse Bone Morphogenetic Protein Receptor Type-1B (BMPR1B) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx690976
Tested Applications
SDS-PAGE
Description
Bone Morphogenetic Protein Receptor Type-1B (BMPR1B) protein is a recombinant Mouse protein expressed in HEK293 cells.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Bone Morphogenetic Protein Receptor Type-1B (BMPR1B) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Lys14-Lys126 Tag: C-terminal Fc tag |
| Origin | Mouse |
| Observed MW | 39.4 kDa |
| Expression | Recombinant |
| Purity | > 88.3+9.9% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P36898 |
| NCBI Accession | NP_031586.1 |
| Alias | BMP type-1B receptor,BMPR-1BALK6,AMD3,AMDD,BDA2,ALK-6,BDA1D,CDw293 |
| Background | Protein BMPR1B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
Bone morphogenetic protein receptor type 1B (BMPR1B) is a serine/threonine kinase receptor that plays a central role in mediating the effects of bone morphogenetic proteins (BMPs), which are part of the transforming growth factor-beta (TGF-β) superfamily. BMPs are critical regulators of cell growth, differentiation, development, and tissue repair. BMPR1B specifically binds BMP ligands, initiating signaling pathways that drive cellular responses crucial for skeletal development, cartilage formation, and neural differentiation. Unlike BMPR1A, which has broader expression and interacts with a range of BMPs, BMPR1B expression is more restricted, and it is particularly important in cartilage development and chondrogenesis.
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