Mouse Bcl2 Associated X Protein (BAX) CLIA Kit
643.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Bcl2 Associated X Protein (BAX) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195232
tested applications
CLIA
Description
Mouse Bcl-2 Associated X Protein (Bax) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Bcl-2 Associated X Protein (Bax).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Bcl2 Associated X Protein (BAX) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.2 pg/ml - 2000 pg/ml |
| Sensitivity | 18.8 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | BAX,BCL2L4,BCL2 associated X protein,Bcl-2-like protein 4,Bcl2-L-4 |
| Background | CLIA Kits BAX |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
BCL2 associated X, apoptosis regulator (BAX) is a pro-apoptotic protein that plays a critical role in mitochondrial-mediated apoptosis, a key process in regulating cell death BAX is activated in response to various stress signals, including DNA damage and oxidative stress, and it translocates to the mitochondria, where it promotes the release of cytochrome c, leading to the activation of caspases and cell death BAX functions as a counterpart to anti-apoptotic proteins like BCL2, which inhibit apoptosis BAX's activity is tightly regulated, as excessive activation can lead to uncontrolled cell death and tissue damage Its dysregulation has been implicated in several diseases, including cancer, where reduced BAX activity allows tumor cells to evade apoptosis, contributing to tumor progression and resistance to therapy BAX also has a role in regulating immune responses, particularly in T-cell development and survival, making it crucial for immune system homeostasis Additionally, BAX is involved in neurodegenerative diseases, where excessive cell death in neurons leads to conditions like Alzheimer's and Parkinson's
Related Products
Guinea pig Bax(Bcl-2 Associated X Protein) ELISA Kit
Ver Producto
Human BAX(Apoptosis regulator BAX) ELISA Kit
Ver Producto