Mouse ATP Binding Cassette Transporter C3 (ABCC3) ELISA Kit

Este producto es parte de ABCC - ATP binding cassette subfamily C
Mouse ATP Binding Cassette Transporter C3 (ABCC3) ELISA Kit

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935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits ABCC3

proveedor

Abbexa

reference

abx254851

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse ATP Binding Cassette Transporter C3 (ABCC3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Canalicular multispecific organic anion transporter 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ABCC3, also known as multidrug resistance-associated protein 3 (MRP3), is expressed on the basolateral membrane of hepatocytes, enterocytes, and other epithelial cells. It facilitates the efflux of organic anions, including bile acids, glucuronides, and sulfated metabolites, from cells into the bloodstream for subsequent excretion via the kidneys. ABCC3 is upregulated in conditions where bile flow is impaired, such as cholestasis, serving as a compensatory mechanism to reduce intracellular bile acid toxicity. It also transports drug conjugates and metabolites, playing a critical role in drug resistance and disposition. ABCC3 is highly expressed in tissues such as the liver, intestines, and pancreas, where it contributes to detoxification and cellular protection. Dysregulation of ABCC3 has been linked to altered drug pharmacokinetics and resistance to chemotherapy.

Características del producto

category

ELISA Kits


immunogen target

ATP Binding Cassette Transporter C3 (ABCC3)


reactivity

Mouse


test range

78 pg/ml - 5000 pg/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

ABC31,EST90757,MLP2,Multidrug resistance-associated protein 3


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

ABCC3


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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