Mouse ATP Binding Cassette Transporter B9 (ABCB9) Protein

Este producto es parte de ABCB - ATP binding cassette subfamily B member
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221€ (10 µg)

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935106861
info@markelab.com
name
Mouse ATP Binding Cassette Transporter B9 (ABCB9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650387
tested applications
WB, SDS-PAGE

Description

Mouse ABCB9 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
ATP Binding Cassette Transporter B9 (ABCB9)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 32.5 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Val500-Ala762
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9JJ59
Alias
EST122234,TAPL
Background
Protein ABCB9
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ABCB9, also known as TAPL (Transporter Associated with Antigen Processing-Like), is an ATP-binding cassette transporter localized to lysosomes and late endosomes. It plays a role in the transport of peptides into lysosomal compartments, contributing to processes such as antigen presentation and lysosomal proteostasis. ABCB9 contains two nucleotide-binding domains and transmembrane regions that mediate ATP-dependent peptide transport. It is expressed in various tissues, with higher levels in immune-related cells, where it supports lysosomal function and immune responses. Although its precise physiological substrates and roles remain under investigation, ABCB9’s involvement in lysosomal function underscores its importance in cellular homeostasis, immune regulation, and protein degradation pathways.

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