Mouse ATP Binding Cassette Transporter A6 (ABCA6) Protein

Este producto es parte de ABCA6 - ATP Binding Cassette Transporter A6
Mouse ATP Binding Cassette Transporter A6 (ABCA6) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ABCA6

proveedor

Abbexa

reference

abx650395

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse ABCA6 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

ABCA6 is an ATP-binding cassette transporter that is thought to be involved in lipid metabolism and cholesterol transport, although its exact substrates and physiological roles are not fully characterized. It is primarily expressed in tissues such as the liver, macrophages, and vascular endothelial cells, where it may participate in lipid efflux and reverse cholesterol transport. ABCA6 shares structural similarities with other members of the ABCA subfamily, containing two transmembrane domains and two nucleotide-binding domains that facilitate ATP-driven substrate translocation. Dysregulation of ABCA6 expression has been associated with metabolic syndromes and cardiovascular diseases, suggesting its involvement in lipid-related disorders. Further research is needed to elucidate its specific functions in cellular lipid handling and disease progression.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

ATP Binding Cassette Transporter A6 (ABCA6)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 28.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val1398-Lys1616 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ABCA6


dry ice

No


availability

Shipped within 5-7 working days.


alias

EST155051


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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