Mouse ATP Binding Cassette Transporter A6 (ABCA6) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein ABCA6
proveedor
Abbexareference
abx650395Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ABCA6 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
ABCA6 is an ATP-binding cassette transporter that is thought to be involved in lipid metabolism and cholesterol transport, although its exact substrates and physiological roles are not fully characterized. It is primarily expressed in tissues such as the liver, macrophages, and vascular endothelial cells, where it may participate in lipid efflux and reverse cholesterol transport. ABCA6 shares structural similarities with other members of the ABCA subfamily, containing two transmembrane domains and two nucleotide-binding domains that facilitate ATP-driven substrate translocation. Dysregulation of ABCA6 expression has been associated with metabolic syndromes and cardiovascular diseases, suggesting its involvement in lipid-related disorders. Further research is needed to elucidate its specific functions in cellular lipid handling and disease progression.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
ATP Binding Cassette Transporter A6 (ABCA6)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 28.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val1398-Lys1616 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ABCA6
dry ice
No
availability
Shipped within 5-7 working days.
alias
EST155051
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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