Mouse ATP Binding Cassette Transporter A6 (ABCA6) Protein

Este producto es parte de ABCA6 - ATP Binding Cassette Transporter A6
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221€ (10 µg)

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935106861
info@markelab.com
name
Mouse ATP Binding Cassette Transporter A6 (ABCA6) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650395
tested applications
WB, SDS-PAGE

Description

Mouse ABCA6 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
ATP Binding Cassette Transporter A6 (ABCA6)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 28.2 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Val1398-Lys1616
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8K441
Alias
EST155051
Background
Protein ABCA6
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ABCA6 is an ATP-binding cassette transporter that is thought to be involved in lipid metabolism and cholesterol transport, although its exact substrates and physiological roles are not fully characterized. It is primarily expressed in tissues such as the liver, macrophages, and vascular endothelial cells, where it may participate in lipid efflux and reverse cholesterol transport. ABCA6 shares structural similarities with other members of the ABCA subfamily, containing two transmembrane domains and two nucleotide-binding domains that facilitate ATP-driven substrate translocation. Dysregulation of ABCA6 expression has been associated with metabolic syndromes and cardiovascular diseases, suggesting its involvement in lipid-related disorders. Further research is needed to elucidate its specific functions in cellular lipid handling and disease progression.

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