ATP Binding Cassette Transporter A6 (ABCA6) Antibody
52€ (10 µg)
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935106861
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name
ATP Binding Cassette Transporter A6 (ABCA6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014227
tested applications
WB
Description
Rabbit polyclonal antibody against ABCA6 protein. Immunogen region is C-terminal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Transporter A6 (ABCA6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N139 |
| Alias | EST155051 |
| Background | Antibody anti-ABCA6 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ABCA6 is an ATP-binding cassette transporter that is thought to be involved in lipid metabolism and cholesterol transport, although its exact substrates and physiological roles are not fully characterized. It is primarily expressed in tissues such as the liver, macrophages, and vascular endothelial cells, where it may participate in lipid efflux and reverse cholesterol transport. ABCA6 shares structural similarities with other members of the ABCA subfamily, containing two transmembrane domains and two nucleotide-binding domains that facilitate ATP-driven substrate translocation. Dysregulation of ABCA6 expression has been associated with metabolic syndromes and cardiovascular diseases, suggesting its involvement in lipid-related disorders. Further research is needed to elucidate its specific functions in cellular lipid handling and disease progression.
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