Mouse ATP Binding Cassette Transporter A5 (ABCA5) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein ABCA5
proveedor
Abbexareference
abx650394Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ABCA5 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
ABCA5 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid transport and cellular detoxification processes. It is expressed in various tissues, including the liver, kidney, and brain, where it plays a role in maintaining lipid homeostasis and protecting cells from oxidative stress. ABCA5 utilizes ATP hydrolysis to transport lipids across membranes, contributing to processes such as cholesterol efflux and intracellular lipid trafficking. It is also associated with the regulation of lysosomal function and autophagy. Dysregulation of ABCA5 has been linked to lysosomal storage disorders and neurodegenerative diseases, highlighting its role in cellular clearance mechanisms and homeostasis.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
ATP Binding Cassette Transporter A5 (ABCA5)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 31.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val1401-Phe1642 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ABCA5
dry ice
No
availability
Shipped within 5-7 working days.
alias
ABC13,HTC3
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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proveedor
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