Mouse ATP Binding Cassette Transporter A5 (ABCA5) Protein

Este producto es parte de ABCA5 - ATP Binding Cassette Transporter A5
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221€ (10 µg)

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935106861
info@markelab.com
name
Mouse ATP Binding Cassette Transporter A5 (ABCA5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650394
tested applications
WB, SDS-PAGE

Description

Mouse ABCA5 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
ATP Binding Cassette Transporter A5 (ABCA5)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 31.5 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Val1401-Phe1642
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8K448
Alias
ABC13,HTC3
Background
Protein ABCA5
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ABCA5 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid transport and cellular detoxification processes. It is expressed in various tissues, including the liver, kidney, and brain, where it plays a role in maintaining lipid homeostasis and protecting cells from oxidative stress. ABCA5 utilizes ATP hydrolysis to transport lipids across membranes, contributing to processes such as cholesterol efflux and intracellular lipid trafficking. It is also associated with the regulation of lysosomal function and autophagy. Dysregulation of ABCA5 has been linked to lysosomal storage disorders and neurodegenerative diseases, highlighting its role in cellular clearance mechanisms and homeostasis.

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