ATP Binding Cassette Transporter A5 (ABCA5) Antibody
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935106861
info@markelab.com
Precio
357.5€ (100 µg)
Antibody anti-ABCA5
proveedor
Abbexareference
abx038247Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Rabbit Polyclonal against the ABCA5 protein.
Background
ABCA5 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid transport and cellular detoxification processes. It is expressed in various tissues, including the liver, kidney, and brain, where it plays a role in maintaining lipid homeostasis and protecting cells from oxidative stress. ABCA5 utilizes ATP hydrolysis to transport lipids across membranes, contributing to processes such as cholesterol efflux and intracellular lipid trafficking. It is also associated with the regulation of lysosomal function and autophagy. Dysregulation of ABCA5 has been linked to lysosomal storage disorders and neurodegenerative diseases, highlighting its role in cellular clearance mechanisms and homeostasis.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
ATP Binding Cassette Transporter A5 (ABCA5)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Lyophilized
tested applications
ELISA, WB, IHC
purification
Purified by antigen affinity column chromatography.
recommended dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
size 1
100 µg
size 2
1 mg
storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
or code
ABCA5
dry ice
No
availability
Shipped within 7-15 working days.
alias
ABC13,HTC3
NCBI accession
NM_018672
note
Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -
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
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
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ELISA, WB, IHCreactivity
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