ATP Binding Cassette Transporter A5 (ABCA5) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
ATP Binding Cassette Transporter A5 (ABCA5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037916
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ABCA5 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Transporter A5 (ABCA5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WWZ7-2 |
| Alias | ABC13,HTC3 |
| Background | Antibody anti-ABCA5 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ABCA5 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid transport and cellular detoxification processes. It is expressed in various tissues, including the liver, kidney, and brain, where it plays a role in maintaining lipid homeostasis and protecting cells from oxidative stress. ABCA5 utilizes ATP hydrolysis to transport lipids across membranes, contributing to processes such as cholesterol efflux and intracellular lipid trafficking. It is also associated with the regulation of lysosomal function and autophagy. Dysregulation of ABCA5 has been linked to lysosomal storage disorders and neurodegenerative diseases, highlighting its role in cellular clearance mechanisms and homeostasis.
Related Products
Recombinant Human ABCA5
Ver Producto
ATP Binding Cassette Transporter A5 (ABCA5) Antibody
Rabbit Polyclonal against the ABCA5 protein.
Ver ProductoATP Binding Cassette Transporter A5 (ABCA5) Antibody
Rabbit Polyclonal against the ABCA5 protein.
Ver Producto