Mouse ATP Binding Cassette Subfamily B Member 10 (ABCB10) Protein

Este producto es parte de ABCB - ATP binding cassette subfamily B member
Mouse ATP Binding Cassette Subfamily B Member 10 (ABCB10) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ABCB10

proveedor

Abbexa

reference

abx650389

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse ABCB10 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

ABCB10, also known as mitochondrial ABC transporter-2, is primarily localized in the inner mitochondrial membrane and plays a critical role in mitochondrial function and heme biosynthesis. It is involved in transporting substrates required for heme production, a vital component of hemoglobin and cytochromes. ABCB10 works in coordination with other mitochondrial transporters, such as ABCB7, to ensure proper iron-sulfur cluster biogenesis and cellular redox balance. It is highly expressed in tissues with high metabolic and oxygen demands, such as the liver, heart, and erythroid cells. Dysregulation of ABCB10 has been linked to mitochondrial dysfunction and oxidative stress, contributing to conditions such as anemia and cardiovascular diseases. Its role in maintaining mitochondrial health highlights its importance in cellular energy metabolism.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

ATP Binding Cassette Subfamily B Member 10 (ABCB10)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 31.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu457-Ala715 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ABCB10


dry ice

No


availability

Shipped within 5-7 working days.


alias

M-ABC2,MTABC2,EST20237


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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clonality

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