Mouse ATP Binding Cassette Subfamily A Member 8 (ABCA8) Protein

Este producto es parte de ABCA8 - ATP Binding Cassette Transporter A8
Mouse ATP Binding Cassette Subfamily A Member 8 (ABCA8) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ABCA8

proveedor

Abbexa

reference

abx650397

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse ABCA8 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

ABCA8 is a member of the ATP-binding cassette transporter family, primarily involved in lipid transport and xenobiotic metabolism. It is highly expressed in the brain, liver, and kidneys, suggesting roles in lipid homeostasis and the clearance of toxins or drugs. ABCA8 is thought to facilitate the transport of cholesterol and sphingolipids across cellular membranes, contributing to cellular lipid regulation. In the brain, ABCA8 has been implicated in myelin formation and neuronal maintenance, where dysregulation may contribute to neurodegenerative diseases. Mutations or altered expression of ABCA8 have been associated with conditions such as multiple sclerosis and certain cancers. Its role in lipid metabolism and potential involvement in drug resistance highlight its importance in both physiological and pathological processes.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

ATP Binding Cassette Subfamily A Member 8 (ABCA8)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 26.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala1303-Glu1514 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ABCA8


dry ice

No


availability

Shipped within 5-7 working days.


alias

KIAA0822


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reference

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