ATP Binding Cassette Subfamily A Member 8 (ABCA8) Antibody
299€ (100 µl)
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935106861
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name
ATP Binding Cassette Subfamily A Member 8 (ABCA8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx130552
tested applications
WB, IHC, IF/ICC
Description
ABCA8 Antibody is a Rabbit Polyclonal against ABCA8.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Subfamily A Member 8 (ABCA8) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | KIAA0822 |
| Background | Antibody anti-ABCA8 |
| Status | RUO |
Descripción
ABCA8 is a member of the ATP-binding cassette transporter family, primarily involved in lipid transport and xenobiotic metabolism. It is highly expressed in the brain, liver, and kidneys, suggesting roles in lipid homeostasis and the clearance of toxins or drugs. ABCA8 is thought to facilitate the transport of cholesterol and sphingolipids across cellular membranes, contributing to cellular lipid regulation. In the brain, ABCA8 has been implicated in myelin formation and neuronal maintenance, where dysregulation may contribute to neurodegenerative diseases. Mutations or altered expression of ABCA8 have been associated with conditions such as multiple sclerosis and certain cancers. Its role in lipid metabolism and potential involvement in drug resistance highlight its importance in both physiological and pathological processes.
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ATP Binding Cassette Subfamily A Member 8 (ABCA8) Antibody
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ATP Binding Cassette Subfamily A Member 8 (ABCA8) Antibody
ABCA8 Antibody is a Rabbit Polyclonal against ABCA8.
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