Mouse ATP-binding cassette sub-family B member 8, mitochondrial (ABCB8) ELISA Kit

Este producto es parte de ABCB - ATP binding cassette subfamily B member
Product Graph
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse ATP-binding cassette sub-family B member 8, mitochondrial (ABCB8) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500430
tested applications
ELISA

Description

Mouse ATP-binding cassette sub-family B member 8, mitochondrial (ABCB8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ATP-binding cassette sub-family B member 8, mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
ATP-binding cassette sub-family B member 8, mitochondrial (ABCB8)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9CXJ4
Gene ID
74610
Alias
EST328128,M-ABC1,MABC1,MITOSUR
Background
Elisa kits for ABCB8
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ABCB8 is a mitochondrial ATP-binding cassette transporter involved in the export of iron-sulfur cluster intermediates and possibly other substrates from mitochondria to the cytosol. This function is critical for maintaining cellular iron homeostasis, facilitating the proper assembly of iron-sulfur cluster-containing proteins, and regulating oxidative stress. ABCB8 is highly expressed in metabolically active tissues, such as the heart, skeletal muscle, and liver, where mitochondrial function is crucial. Dysregulation of ABCB8 can lead to mitochondrial iron overload, contributing to oxidative damage and cellular dysfunction, particularly in cardiomyocytes. Emerging evidence suggests that ABCB8 plays a protective role in maintaining mitochondrial integrity under stress conditions, making it an important factor in cardiovascular health and mitochondrial-related diseases.

Related Products

abx005962

ATP Binding Cassette Transporter B8 (ABCB8) Antibody

ABCB8 Antibody is a Rabbit Polyclonal Antibody against ABCB8.

Ver Producto
abx038131

ATP Binding Cassette Transporter B8 (ABCB8) Antibody

Rabbit Polyclonal against the ABCB8 protein.

Ver Producto
abx130565

ATP Binding Cassette Transporter B8 (ABCB8) Antibody

ABCB8 Antibody is a Rabbit Polyclonal against ABCB8.

Ver Producto