Mouse ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10) ELISA Kit

Este producto es parte de ABCB - ATP binding cassette subfamily B member
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500433
tested applications
ELISA

Description

Mouse ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ATP-binding cassette sub-family B member 10, mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9JI39
Gene ID
56199
Alias
M-ABC2,MTABC2,EST20237
Background
Elisa kits for ABCB10
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ABCB10, also known as mitochondrial ABC transporter-2, is primarily localized in the inner mitochondrial membrane and plays a critical role in mitochondrial function and heme biosynthesis. It is involved in transporting substrates required for heme production, a vital component of hemoglobin and cytochromes. ABCB10 works in coordination with other mitochondrial transporters, such as ABCB7, to ensure proper iron-sulfur cluster biogenesis and cellular redox balance. It is highly expressed in tissues with high metabolic and oxygen demands, such as the liver, heart, and erythroid cells. Dysregulation of ABCB10 has been linked to mitochondrial dysfunction and oxidative stress, contributing to conditions such as anemia and cardiovascular diseases. Its role in maintaining mitochondrial health highlights its importance in cellular energy metabolism.

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