935106861
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Precio
687.5€ (96 tests)
Mouse ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ATP-binding cassette sub-family B member 10, mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.
ABCB10, also known as mitochondrial ABC transporter-2, is primarily localized in the inner mitochondrial membrane and plays a critical role in mitochondrial function and heme biosynthesis. It is involved in transporting substrates required for heme production, a vital component of hemoglobin and cytochromes. ABCB10 works in coordination with other mitochondrial transporters, such as ABCB7, to ensure proper iron-sulfur cluster biogenesis and cellular redox balance. It is highly expressed in tissues with high metabolic and oxygen demands, such as the liver, heart, and erythroid cells. Dysregulation of ABCB10 has been linked to mitochondrial dysfunction and oxidative stress, contributing to conditions such as anemia and cardiovascular diseases. Its role in maintaining mitochondrial health highlights its importance in cellular energy metabolism.
ELISA Kits
ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10)
Mouse
0.156 ng/ml - 10 ng/ml
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
M-ABC2,MTABC2,EST20237
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ABCB10
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
May mediate critical mitochondrial transport functions related to heme biosynthesis.
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