935106861
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Precio
687.5€ (96 tests)
Mouse Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aryl Hydrocarbon Receptor Repressor (AHRR) concentrations in tissue homogenates, cell lysates and other biological fluids.
AHRR is a transcriptional repressor that negatively regulates the AHR signaling pathway. It is induced by AHR activation as part of a negative feedback loop and functions by competing with AHR for dimerization with ARNT or binding to XREs to inhibit AHR-mediated transcription. AHRR is expressed in various tissues, including the liver, lungs, and immune cells, and is involved in maintaining the balance of AHR activity, preventing excessive or prolonged responses to environmental toxins. Dysregulation of AHRR has been associated with cancer, particularly in lung cancer and gastric cancer, where reduced AHRR expression leads to enhanced AHR activity and tumor-promoting effects. In addition to its role in xenobiotic detoxification, AHRR also participates in regulating immune responses and maintaining cellular homeostasis, with emerging evidence highlighting its involvement in inflammation and metabolic disorders.
ELISA Kits
Aryl Hydrocarbon Receptor Repressor (AHRR)
Mouse
0.156 ng/ml - 10 ng/ml
< 0.06 ng/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
5 × 96 tests
10 × 96 tests
AHH,AHHR,bHLHe77
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
AHRR
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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