Mouse Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1) ELISA Kit

Este producto es parte de AGAP - Arf-GAP with GTPase ANK repeat and PH domain-containing protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501265
tested applications
ELISA

Description

Mouse Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8BXK8
Gene ID
347722
Alias
AGAP-1,CENTG2,GGAP1
Background
Elisa kits for AGAP1
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

AGAP1 is a multifunctional protein involved in regulating endocytic trafficking, cytoskeletal organization, and intracellular signaling. It acts as a GTPase-activating protein (GAP) for Arf family GTPases, facilitating vesicle formation and receptor recycling. Structurally, it contains a GTPase domain, ankyrin repeats for protein-protein interactions, and a PH (pleckstrin homology) domain that enables membrane association. AGAP1 is expressed in various tissues, with high levels in neurons, where it modulates synaptic vesicle trafficking, dendritic spine morphogenesis, and endosomal sorting. Dysregulation of AGAP1 has been linked to neurodevelopmental disorders, cognitive impairments, and cellular transport defects, emphasizing its critical role in neuronal connectivity and function.
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