Mouse Anoctamin-6 (ANO6) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ANO6
proveedor
Abbexareference
abx501830Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Anoctamin-6 (ANO6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anoctamin-6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ANO6, also known as TMEM16F, is a dual-function protein acting as a calcium-activated phospholipid scramblase and ion channel. It plays a critical role in plasma membrane repair, cell death (apoptosis), and blood coagulation by regulating the externalization of phosphatidylserine (PS), a process essential for platelet activation and membrane remodeling. ANO6 is expressed in various tissues, including the hematopoietic system, skeletal muscle, and immune cells. Mutations in ANO6 cause Scott syndrome, a rare bleeding disorder characterized by impaired PS exposure on platelet surfaces, which disrupts proper blood clotting. ANO6 also contributes to cellular responses to mechanical stress, apoptosis, and bone development. Its roles in membrane repair and phospholipid scrambling underscore its importance in cell survival, homeostasis, and coagulation.
Características del producto
category
ELISA Kits
immunogen target
Anoctamin-6 (ANO6)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ANO6,TMEM16F
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ANO6
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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