Human Anoctamin 6 (ANO6) ELISA Kit

Este producto es parte de ANO - Anoctamin
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Anoctamin 6 (ANO6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150674
tested applications
ELISA

Description

Human Anoctamin 6 (ANO6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Anoctamin 6 (ANO6) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Anoctamin 6 (ANO6)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Anoctamin 6 (ANO6)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.12 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
ANO6,TMEM16F
Background
Elisa kits for ANO6
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ANO6, also known as TMEM16F, is a dual-function protein acting as a calcium-activated phospholipid scramblase and ion channel. It plays a critical role in plasma membrane repair, cell death (apoptosis), and blood coagulation by regulating the externalization of phosphatidylserine (PS), a process essential for platelet activation and membrane remodeling. ANO6 is expressed in various tissues, including the hematopoietic system, skeletal muscle, and immune cells. Mutations in ANO6 cause Scott syndrome, a rare bleeding disorder characterized by impaired PS exposure on platelet surfaces, which disrupts proper blood clotting. ANO6 also contributes to cellular responses to mechanical stress, apoptosis, and bone development. Its roles in membrane repair and phospholipid scrambling underscore its importance in cell survival, homeostasis, and coagulation.

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