Mouse Angiomotin-like protein 1 (AMOTL1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Angiomotin-like protein 1 (AMOTL1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx520012
tested applications
ELISA
Description
Mouse Angiomotin-like protein 1 (AMOTL1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Angiomotin-like protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Angiomotin-like protein 1 (AMOTL1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9D4H4 |
| Alias | JEAP |
| Background | Elisa kits for AMOTL1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Angiomotin Like 1 (AMOTL1) is a member of the angiomotin protein family, which is involved in regulating endothelial cell migration, polarity, and vascular stability. AMOTL1 plays a crucial role in maintaining endothelial barrier function and modulating angiogenesis by interacting with tight junction proteins and signaling pathways. It is known to participate in the regulation of the Hippo signaling pathway, where it influences cell proliferation and organ size by interacting with transcriptional regulators such as YAP and TAZ. AMOTL1 is also implicated in tumor progression, as it can modulate cell migration, adhesion, and invasion in cancer cells. Dysregulation of AMOTL1 has been associated with pathological angiogenesis, cancer metastasis, and inflammatory diseases. Its function in maintaining vascular integrity and its interaction with key signaling pathways make AMOTL1 a promising target for therapeutic interventions in vascular disorders and oncology.
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