Human AMOTL1 (Angiomotin-like protein 1) ELISA Kit

Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human AMOTL1 (Angiomotin-like protein 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2206
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.156-10ng/ml |
Sensitivity | 0.094ng/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q8IY63 |
Alias | JEAP |
Background | Elisa kits for AMOTL1 |
Status | RUO |
Angiomotin Like 1 (AMOTL1) is a member of the angiomotin protein family, which is involved in regulating endothelial cell migration, polarity, and vascular stability. AMOTL1 plays a crucial role in maintaining endothelial barrier function and modulating angiogenesis by interacting with tight junction proteins and signaling pathways. It is known to participate in the regulation of the Hippo signaling pathway, where it influences cell proliferation and organ size by interacting with transcriptional regulators such as YAP and TAZ. AMOTL1 is also implicated in tumor progression, as it can modulate cell migration, adhesion, and invasion in cancer cells. Dysregulation of AMOTL1 has been associated with pathological angiogenesis, cancer metastasis, and inflammatory diseases. Its function in maintaining vascular integrity and its interaction with key signaling pathways make AMOTL1 a promising target for therapeutic interventions in vascular disorders and oncology.
Related Products

Human AMOTL1 (Angiomotin-like protein 1) ELISA Kit
Ver Producto
AMOTL1 antibody
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Ver Producto