Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) CLIA Kit

Este producto es parte de AIMP - Aminoacyl tRNA synthetase complex interacting multifunctional protein
Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) CLIA Kit
871€ (96 tests)

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Name
Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) CLIA Kit
Category
CLIA Kits
Provider
Abbexa
Reference
abx495967
Tested Applications
CLIA

Description

Mouse AIMP1 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
CLIA Kits
Immunogen Target
Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
31.2 pg/ml - 2000 pg/ml
Sensitivity
< 11.3 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard: Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma, tissue homogenates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
p43,HLD3,EMAP2,SCYE1,EMAPII
Background
CLIA Kits AIMP1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.  The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.  Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

AIMP1, also known as EMAP II (Endothelial Monocyte-Activating Polypeptide II), is a multifunctional protein that acts as a core component of the multi-aminoacyl-tRNA synthetase complex (MSC), which is essential for protein synthesis. It interacts with various aminoacyl-tRNA synthetases to maintain the stability and functionality of the complex. Beyond its role in translation, AIMP1 has extracellular signaling functions, particularly in modulating immune responses and angiogenesis. When secreted, AIMP1 functions as a cytokine that activates monocytes and endothelial cells, contributing to inflammatory responses and tissue repair. It is also involved in apoptosis, cellular stress responses, and tumor suppression. Dysregulation of AIMP1 is associated with cancer progression, inflammatory diseases, and autoimmune disorders, highlighting its dual roles in intracellular protein synthesis and extracellular signaling.

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