Mouse Aminoacyl tRNA Synthase Complex-Interacting Multifunctional Protein 2 / JTV1 (AIMP2) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse Aminoacyl tRNA Synthase Complex-Interacting Multifunctional Protein 2 / JTV1 (AIMP2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501346
tested applications
ELISA
Description
Mouse Aminoacyl tRNA Synthase Complex-Interacting Multifunctional Protein 2 / JTV1 (AIMP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aminoacyl tRNA Synthase Complex-Interacting Multifunctional Protein 2 / JTV1 (AIMP2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Aminoacyl tRNA Synthase Complex-Interacting Multifunctional Protein 2 / JTV1 (AIMP2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8R010 |
| Gene ID | 231872 |
| Alias | HLD17,JTV-1, JTV1,P38 |
| Background | Elisa kits for AIMP2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AIMP2 is a structural and regulatory protein that stabilizes the multi-aminoacyl-tRNA synthetase complex (MSC) and modulates various cellular processes, including translation, stress responses, and cell cycle regulation. AIMP2 interacts with other aminoacyl-tRNA synthetases to ensure the efficient attachment of amino acids to their corresponding tRNAs. In addition to its translational role, AIMP2 functions as a tumor suppressor, particularly through its isoform AIMP2-DX2, which inhibits cell proliferation and induces apoptosis. Dysregulation of AIMP2 is implicated in cancers, where loss of its tumor-suppressive activity promotes tumor growth and chemoresistance. It is also involved in neurodegenerative diseases such as Parkinson’s disease, where it modulates oxidative stress and neuronal survival. AIMP2’s role in both protein synthesis and cellular homeostasis underscores its importance in health and disease.
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