Mouse Alpha-protein kinase 3 (ALPK3) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Alpha-protein kinase 3 (ALPK3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501590
tested applications
ELISA
Description
Mouse Alpha-protein kinase 3 (ALPK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alpha-protein kinase 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alpha-protein kinase 3 (ALPK3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q924C5 |
| Alias | ALPK3,KIAA1330,MAK |
| Background | Elisa kits for ALPK3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ALPK3 is an alpha-protein kinase involved in critical cellular processes, including cardiac development, sarcomere organization, and metabolic signaling. It is highly expressed in cardiac and skeletal muscle tissues, where it regulates protein phosphorylation necessary for proper contractile function and muscle structure. Mutations in ALPK3 are associated with cardiomyopathies, including dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), due to defects in sarcomere assembly and signaling pathways. ALPK3 has also been shown to interact with AMPK (AMP-activated protein kinase), linking it to energy sensing and metabolic regulation in cardiomyocytes. Beyond its role in cardiac function, ALPK3 may influence cell growth and differentiation, and its dysregulation has been implicated in tumorigenesis. Recent studies suggest that ALPK3 acts as a tumor suppressor in specific cancers, where its loss of function enhances cell proliferation and survival. Its critical roles in cardiac development and cellular metabolism make ALPK3 a promising target for therapeutic intervention in cardiac and metabolic diseases.
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Mouse Alpha-protein kinase 3 (ALPK3) ELISA Kit
Mouse Alpha-protein kinase 3 (ALPK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alpha-protein kinase 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
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