Mouse Alpha Kinase 1 (ALPK1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Alpha Kinase 1 (ALPK1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501586
tested applications
ELISA
Description
Mouse Alpha Kinase 1 (ALPK1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alpha Kinase 1 (ALPK1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alpha Kinase 1 (ALPK1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.05 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9CXB8 |
| Alias | Lymphocyte alpha-protein kinase |
| Background | Elisa kits for ALPK1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Alpha-Protein Kinase 1 (ALPK1) is a serine/threonine kinase belonging to the alpha-protein kinase family, characterized by its atypical catalytic domain structure. ALPK1 plays a role in various cellular processes, including protein trafficking, inflammation, and innate immune signaling. It is involved in the Golgi-to-endoplasmic reticulum (ER) transport pathway and has been implicated in the regulation of vesicle trafficking. ALPK1 is also recognized as a critical mediator of inflammatory responses, where it activates signaling pathways such as NF-kB and MAPK in response to pathogenic stimuli. Genetic mutations or dysregulation of ALPK1 have been associated with inflammatory diseases, including gouty arthritis and familial autoinflammatory conditions such as ALPK1-associated autoinflammatory syndrome. In addition, emerging evidence suggests that ALPK1 may contribute to tumorigenesis through its role in cellular signaling and inflammation. Therapeutic strategies targeting ALPK1 are being explored to modulate inflammation and immune responses, with potential implications for treating inflammatory and autoimmune diseases.
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