Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx501371
Tested Applications
ELISA
Description
Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.39 ng/ml - 25 ng/ml |
| Sensitivity | < 0.17 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9JII6 |
| Gene ID | 58810 |
| Alias | AKR1A1, ALDR1, ALR,ARM, DD3 |
| Background | Elisa Kits for: AKR1A1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
AKR1A1 is a widely expressed enzyme that belongs to the aldo-keto reductase superfamily. It catalyzes the reduction of aldehydes and ketones to their respective alcohols using NADPH as a cofactor, playing a key role in detoxifying reactive aldehydes generated during lipid peroxidation and metabolism. AKR1A1 is involved in the metabolism of endogenous compounds, such as prostaglandins, steroids, and lipid-derived aldehydes, as well as exogenous toxins, including chemotherapeutics and environmental pollutants. AKR1A1 has significant antioxidant properties due to its ability to reduce harmful aldehydes, thus protecting cells from oxidative stress. It also contributes to glucose metabolism by participating in the sorbitol pathway, particularly in the liver, kidneys, and lens. Dysregulation of AKR1A1 is implicated in metabolic disorders, including diabetic complications, cataract formation, and cardiovascular diseases. Additionally, AKR1A1 has been shown to play a role in drug resistance by metabolizing chemotherapeutic agents, making it a target for improving cancer treatments.
Productos relacionados
Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) Antibody
Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) Antibody is a Rabbit Polyclonal antibody against Aldo-Keto Reductase Fam…
Ver producto
Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) Antibody
Rabbit polyclonal antibody against Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) protein. Immunogen region is C-termin…
Ver producto
Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) Antibody
Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) is a member of the aldo/keto reductase superfamily, which consists of mo…
Ver producto