Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) ELISA Kit

Este producto es parte de AKR1A - Aldo-keto reductase family 1 member A
Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AKR1A1

proveedor

Abbexa

reference

abx501371

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

AKR1A1 is a widely expressed enzyme that belongs to the aldo-keto reductase superfamily. It catalyzes the reduction of aldehydes and ketones to their respective alcohols using NADPH as a cofactor, playing a key role in detoxifying reactive aldehydes generated during lipid peroxidation and metabolism. AKR1A1 is involved in the metabolism of endogenous compounds, such as prostaglandins, steroids, and lipid-derived aldehydes, as well as exogenous toxins, including chemotherapeutics and environmental pollutants. AKR1A1 has significant antioxidant properties due to its ability to reduce harmful aldehydes, thus protecting cells from oxidative stress. It also contributes to glucose metabolism by participating in the sorbitol pathway, particularly in the liver, kidneys, and lens. Dysregulation of AKR1A1 is implicated in metabolic disorders, including diabetic complications, cataract formation, and cardiovascular diseases. Additionally, AKR1A1 has been shown to play a role in drug resistance by metabolizing chemotherapeutic agents, making it a target for improving cancer treatments.

Características del producto

category

ELISA Kits


immunogen target

Aldo-Keto Reductase Family 1 Member A1 (AKR1A1)


reactivity

Mouse


test range

0.39 ng/ml - 25 ng/ml


sensitivity

< 0.17 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

AKR1A1, ALDR1, ALR,ARM, DD3


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AKR1A1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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