Mouse Alanine Glyoxylate Aminotransferase 2 (AGXT2) Protein

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221€ (10 µg)

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935106861
info@markelab.com
name
Mouse Alanine Glyoxylate Aminotransferase 2 (AGXT2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650509
tested applications
WB, SDS-PAGE

Description

Mouse AGXT2 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Alanine Glyoxylate Aminotransferase 2 (AGXT2)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 35.6 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Met226-Lys513

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q3UEG6
Alias
AGXT2, AGT2
Background
Protein AGXT2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Alanine-glyoxylate aminotransferase 2 (AGXT2) is a mitochondrial enzyme that participates in the metabolism of amino acids, including the reversible conversion of glyoxylate and alanine to pyruvate and glycine. AGXT2 plays a role in cardiovascular health by metabolizing dimethylarginines, including asymmetric dimethylarginine (ADMA), an inhibitor of nitric oxide synthase and a biomarker for cardiovascular diseases. By reducing ADMA levels, AGXT2 contributes to the regulation of nitric oxide production and endothelial function. Dysregulation of AGXT2 is implicated in hypertension, atherosclerosis, and metabolic syndromes. In addition, AGXT2's role in glyoxylate metabolism links it to oxalate production, suggesting potential contributions to kidney stone formation and renal dysfunction in certain pathological contexts.

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