Mouse Agouti Related Protein (AgRP) CLIA Kit
643.5€ (96 tests)
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name
Mouse Agouti Related Protein (AgRP) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195072
tested applications
CLIA
Description
Mouse Agouti Related Protein (AgRP) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Agouti Related Protein (AgRP).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Agouti Related Protein (AgRP) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 7.81 pg/ml - 500 pg/ml |
| Sensitivity | 4.69 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AGRT,ART,ASIP2 |
| Background | CLIA Kits AGRP |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Agouti-related neuropeptide (AGRP) is a peptide hormone primarily produced in the arcuate nucleus of the hypothalamus in the brain. AGRP plays a crucial role in regulating appetite and energy balance by acting as an antagonist to the melanocortin receptors, particularly the melanocortin-4 receptor (MC4R). By inhibiting MC4R activity, AGRP increases appetite and promotes feeding behavior, leading to weight gain and adiposity. Dysregulation of AGRP signaling has been in obesity and metabolic disorders. Additionally, AGRP neurons are sensitive to nutritional cues and hormonal signals, allowing them to integrate various inputs to modulate feeding behavior accordingly. Pharmacological targeting of AGRP signaling holds promise for the treatment of obesity and related metabolic conditions. Research into the molecular mechanisms underlying AGRP function provides insights into appetite regulation and potential therapeutic avenues for obesity management. Ongoing studies continue to elucidate the complex roles of AGRP in energy homeostasis and metabolic health.
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