Mouse Adenylate kinase 7 (AK7) ELISA Kit
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Description
Mouse Adenylate kinase 7 (AK7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Adenylate kinase 7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Adenylate kinase 7 (AK7) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9D2H2 |
| Gene ID | 78801 |
| Alias | CFAP75,FAP75,SPGF27 |
| Background | Elisa kits for AK7 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AK7 is a cytosolic and cytoskeletal-associated isoform uniquely involved in energy homeostasis and the regulation of ciliary function. AK7 is expressed predominantly in ciliated tissues, such as the respiratory epithelium, reproductive tract, and central nervous system. It has been identified as a crucial protein for cilia stabilization and energy supply, where it maintains ATP levels necessary for ciliary beating and motility. Mutations in AK7 are linked to primary ciliary dyskinesia (PCD), a condition characterized by impaired cilia function leading to chronic respiratory infections, reduced mucociliary clearance, and male infertility. AK7 has also been implicated in neurodegenerative processes, as defects in energy metabolism can disrupt cellular homeostasis in neurons. Beyond ciliary function, AK7 is associated with cellular stress responses, where it regulates energy distribution during high-energy demands. Its involvement in maintaining cytoskeletal integrity and supporting ATP synthesis highlights its broader role in cellular motility and division, particularly in tissues with high turnover or mechanical activity.
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