Mouse Adenylate Cyclase 4 (ADCY4) Protein

Este producto es parte de ADCY - Adenylate Cyclase Type
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234€ (10 µg)

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935106861
info@markelab.com
name
Mouse Adenylate Cyclase 4 (ADCY4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167316
tested applications
WB, SDS-PAGE

Description

Mouse Adenylate Cyclase 4 Protein is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Adenylate Cyclase 4 (ADCY4)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 24.6 kDa  Observed MW (SDS-PAGE): 27 kDa
Concentration: Prior to lyophilization: 80 µg/ml
Sequence Fragment: Ile352-Val541
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q91WF3
Alias
AC4
Background
Protein ADCY4
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADCY4 is expressed in various tissues, including the brain, heart, and lungs. As a member of the adenylate cyclase family, it catalyzes the conversion of ATP to cAMP, an important signaling molecule in cellular responses. ADCY4 is activated by G-proteins and forskolin but is not sensitive to calcium/calmodulin regulation. It plays critical roles in signal transduction pathways involved in neurotransmission, immune response, and cardiovascular functions. Studies suggest that alterations in ADCY4 activity may contribute to inflammatory processes and neurological dysfunction.

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