Adenylate Cyclase 4 (ADCY4) Antibody
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935106861
info@markelab.com
Precio
250€ (80 µl)
Antibody anti-ADCY4
proveedor
Abbexareference
abx034551Tested Applications
ELISA, WB, FCMreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.
Background
ADCY4 is expressed in various tissues, including the brain, heart, and lungs. As a member of the adenylate cyclase family, it catalyzes the conversion of ATP to cAMP, an important signaling molecule in cellular responses. ADCY4 is activated by G-proteins and forskolin but is not sensitive to calcium/calmodulin regulation. It plays critical roles in signal transduction pathways involved in neurotransmission, immune response, and cardiovascular functions. Studies suggest that alterations in ADCY4 activity may contribute to inflammatory processes and neurological dysfunction.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Adenylate Cyclase 4 (ADCY4)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, FCM
purification
Purified through a protein A column, followed by peptide affinity purification.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ADCY4
dry ice
No
availability
Shipped within 5-10 working days.
alias
AC4
uniprot id
note
This product is for research use only.
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