Adenylate Cyclase 4 (ADCY4) Antibody
52€ (10 µg)
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935106861
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name
Adenylate Cyclase 4 (ADCY4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013895
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against ADCY4 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adenylate Cyclase 4 (ADCY4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFM4 |
| Alias | AC4 |
| Background | Antibody anti-ADCY4 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ADCY4 is expressed in various tissues, including the brain, heart, and lungs. As a member of the adenylate cyclase family, it catalyzes the conversion of ATP to cAMP, an important signaling molecule in cellular responses. ADCY4 is activated by G-proteins and forskolin but is not sensitive to calcium/calmodulin regulation. It plays critical roles in signal transduction pathways involved in neurotransmission, immune response, and cardiovascular functions. Studies suggest that alterations in ADCY4 activity may contribute to inflammatory processes and neurological dysfunction.
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