Mouse ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503072
tested applications
ELISA
Description
Mouse ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ADAMTS-Like Protein 2 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ADAMTS-Like Protein 2 (ADAMTSL2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | < 0.42 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q7TSK7 |
| Gene ID | 77794 |
| Alias | KIAA0605,ADAMTSL-2 |
| Background | Elisa kits for ADAMTSL2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADAMTSL2 is an extracellular glycoprotein known for its role in ECM organization and fibrillin microfibril regulation. Mutations in the ADAMTSL2 gene have been linked to Geleophysic dysplasia, a rare autosomal recessive disorder characterized by short stature, joint contractures, and cardiac valvular defects. ADAMTSL2 interacts with fibrillin-1 and modulates TGF-β signaling, critical for connective tissue homeostasis. Its abnormal activity or deficiency can lead to excessive TGF-β signaling, contributing to developmental abnormalities. ADAMTSL2 is widely expressed in connective tissues, including cartilage, bone, and cardiovascular structures, reflecting its importance in ECM stability and integrity.
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