Human ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit

Este producto es parte de ADAMTSL - ADAMTS-like protein
Human ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ADAMTSL2

proveedor

Abbexa

reference

abx503071

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAMTS-Like Protein 2 (ADAMTSL2) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.


Background

ADAMTSL2 is an extracellular glycoprotein known for its role in ECM organization and fibrillin microfibril regulation. Mutations in the ADAMTSL2 gene have been linked to Geleophysic dysplasia, a rare autosomal recessive disorder characterized by short stature, joint contractures, and cardiac valvular defects. ADAMTSL2 interacts with fibrillin-1 and modulates TGF-β signaling, critical for connective tissue homeostasis. Its abnormal activity or deficiency can lead to excessive TGF-β signaling, contributing to developmental abnormalities. ADAMTSL2 is widely expressed in connective tissues, including cartilage, bone, and cardiovascular structures, reflecting its importance in ECM stability and integrity.

Características del producto

category

ELISA Kits


immunogen target

ADAMTS-Like Protein 2 (ADAMTSL2)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.15 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

KIAA0605,ADAMTSL-2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ADAMTSL2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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