Human ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADAMTSL2
proveedor
Abbexareference
abx503071Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human ADAMTS-Like Protein 2 (ADAMTSL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAMTS-Like Protein 2 (ADAMTSL2) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
ADAMTSL2 is an extracellular glycoprotein known for its role in ECM organization and fibrillin microfibril regulation. Mutations in the ADAMTSL2 gene have been linked to Geleophysic dysplasia, a rare autosomal recessive disorder characterized by short stature, joint contractures, and cardiac valvular defects. ADAMTSL2 interacts with fibrillin-1 and modulates TGF-β signaling, critical for connective tissue homeostasis. Its abnormal activity or deficiency can lead to excessive TGF-β signaling, contributing to developmental abnormalities. ADAMTSL2 is widely expressed in connective tissues, including cartilage, bone, and cardiovascular structures, reflecting its importance in ECM stability and integrity.
Características del producto
category
ELISA Kits
immunogen target
ADAMTS-Like Protein 2 (ADAMTSL2)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.15 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
KIAA0605,ADAMTSL-2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADAMTSL2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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